BDBM46106 6-hydroxy-4-keto-N-phenyl-2-thioxo-1H-pyrimidine-5-carboxamide::6-hydroxy-4-oxo-N-phenyl-2-sulfanylidene-1H-pyrimidine-5-carboxamide::6-oxidanyl-4-oxidanylidene-N-phenyl-2-sulfanylidene-1H-pyrimidine-5-carboxamide::CHEMBL1765797::UPDDI-00294859::cid_3000671

SMILES Oc1[nH]c(=S)[nH]c(=O)c1C(=O)Nc1ccccc1

InChI Key InChIKey=GFYRZTLCYQQVHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 46106   

TargetSerine/threonine-protein kinase PLK1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM46106(cid_3000671 | UPDDI-00294859 | CHEMBL1765797 | 6-o...)
Affinity DataIC50: 5.00E+4nMAssay Description:List of compounds to be tested: 33 component starting materials and chemical analogs of the hits identified in the in vitro PLK1-PBD binding primary ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetDNA topoisomerase 2-alpha(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM46106(cid_3000671 | UPDDI-00294859 | CHEMBL1765797 | 6-o...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pHOT DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed