BDBM4605 1,6-naphthyridine deriv. 7::1-(7-amino-3-phenyl-1,6-naphthyridin-2-yl)-3-ethylurea::N-(7-Amino-3-phenyl-1,6-naphthyridin-2-yl)-N-ethyl urea

SMILES CCNC(=O)Nc1nc2cc(N)ncc2cc1-c1ccccc1

InChI Key InChIKey=GJXAKRCIKXUHFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4605   

TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM4605(N-(7-Amino-3-phenyl-1,6-naphthyridin-2-yl)-N-ethyl...)
Affinity DataIC50: 1.30E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM4605(N-(7-Amino-3-phenyl-1,6-naphthyridin-2-yl)-N-ethyl...)
Affinity DataIC50: 7.70E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM4605(N-(7-Amino-3-phenyl-1,6-naphthyridin-2-yl)-N-ethyl...)
Affinity DataIC50: 5.10E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed