BDBM458745 US10758539, Compound 16::US11369611, Compound 16

SMILES COc1cc2ncnc(Oc3ccc4n(C(=O)Nc5ccccc5C(F)(F)F)c(C)cc4c3F)c2cc1OC

InChI Key InChIKey=XFNNNBKHXXBNDZ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458745   

TargetVascular endothelial growth factor receptor 2(Human)
Kala Pharmaceuticals

US Patent
LigandPNGBDBM458745(US10758539, Compound 16 | US11369611, Compound 16)
Affinity DataKd:  5.60E+4nMAssay Description:A competition binding assay was used to measure the ability of a compound to compete for binding of an immobilized adenosine triphosphosphate (ATP) s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Kala Pharmaceuticals

US Patent
LigandPNGBDBM458745(US10758539, Compound 16 | US11369611, Compound 16)
Affinity DataKd:  5.60E+4nMAssay Description:A VEGFR2 tagged T7 phage strain was prepared in an Escherichia coli (E. coli) derived from the BL21 strain. The E. coli were grown to log-phase, infe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent