BDBM458493 4-((benzyloxy)amino)-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazin-2-amine::US10745383, Example 8

SMILES FC(F)(F)c1cccc(n1)-c1nc(NOCc2ccccc2)nc(Nc2ccnc(c2)C(F)(F)F)n1

InChI Key InChIKey=DZDDIUOGNNJMLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 458493   

TargetIsocitrate dehydrogenase [NADP], mitochondrial [40-452,R172K](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM458493(4-((benzyloxy)amino)-6-(6-(trifluoromethyl)pyridin...)
Affinity DataIC50: 239nMAssay Description:The inhibitory activity of a compound against IDH2 (R172K, 40-end) was determined by the decrease of a helper factor NADPH. The test compound was pre...More data for this Ligand-Target Pair
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Date in BDB:
4/13/2021
Entry Details
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