BDBM458106 US10752613, Compound Formula (Ii)::US11161835, Compound Formula (Ii)

SMILES Oc1cc([nH]n1)-c1ccc(NC(=O)c2c(O)[nH]c(=O)[nH]c2=O)cc1

InChI Key InChIKey=KTZORZUQERPKAO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 458106   

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandPNGBDBM458106(US10752613, Compound Formula (Ii) | US11161835, Co...)
Affinity DataIC50: 9.10E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458106(US10752613, Compound Formula (Ii) | US11161835, Co...)
Affinity DataIC50: 1.30E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458106(US10752613, Compound Formula (Ii) | US11161835, Co...)
Affinity DataIC50: 1.30E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent