BDBM458100 US10752613, Compound Formula (Ic)

SMILES Oc1[nH]c(=O)[nH]c(=O)c1C(=O)Nc1ccc(cc1)-c1nn[nH]c1-c1ccccc1

InChI Key InChIKey=OGICGTUMLCCOMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458100   

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandPNGBDBM458100(US10752613, Compound Formula (Ic))
Affinity DataIC50: 110nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458100(US10752613, Compound Formula (Ic))
Affinity DataIC50: 1.22E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent