BDBM458080 Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(7-(4-methoxybenzyl)-4-methyl-2,3-dihydro-1H-indene-5-yl)tetrahydro-2H-pyran-3,4,5-triol::US10752604, Example 1

SMILES COc1ccc(cc1)C(=O)c1cc([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(C)c2CCCc12

InChI Key InChIKey=REJMSFLNFHECHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458080   

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458080(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50: 9.10nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458080(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50: 1.30nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent