BDBM457827 USRE48150, Compound 23

SMILES Brc1cn(cn1)-c1ccnc(c1)C(=O)Nc1csc(c1)-c1nncn1C1CC1

InChI Key InChIKey=LICDVWUXDMKGCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457827   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gilead Sciences

US Patent
LigandPNGBDBM457827(USRE48150, Compound 23)
Affinity DataIC50: 7.49E+5nMAssay Description:The ability of compounds to inhibit ASK1 kinase activity was determined using a time resolved fluorescence resonance energy transfer [TR-FRET] assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent