BDBM457825 USRE48150, Compound 21

SMILES COc1ccc(cc1C(=O)Nc1csc(c1)-c1nncn1C1CC1)-n1cnc(c1)C1CC1

InChI Key InChIKey=VLQPKPCJTAVPON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457825   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gilead Sciences

US Patent
LigandPNGBDBM457825(USRE48150, Compound 21)
Affinity DataIC50: 9.20E+4nMAssay Description:The ability of compounds to inhibit ASK1 kinase activity was determined using a time resolved fluorescence resonance energy transfer [TR-FRET] assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent