BDBM457783 US10738074, Example 14

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)O[C@@H]3[C@H](O)[C@@H](COP(S)(=O)O[C@@H]1[C@@H]2O)O[C@H]3n1cnc2c(N)ncnc12

InChI Key InChIKey=PKAHBTVBEAKIQP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457783   

LigandPNGBDBM457783(US10738074, Example 14)
Affinity DataEC50:  1.90nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM457783(US10738074, Example 14)
Affinity DataEC50:  2.40nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent