BDBM457775 2-amino-9-[(1R,6R,8R,9R,14S,16R,17R,18R)-16- (6-amino-9H-purin-9-yl)-17-azido-3,11,18- trihydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa- 3,11-diphosphatricyclo[12.2.1.16,9]octadec-8-yl]- 1,9-dihydro-6H-purin-6-one::US10738074, Example 6

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]3[C@@H](O[C@H](COP(O)(=O)O[C@@H]1[C@@H]2O)[C@H]3N=[N+]=[N-])n1cnc2c(N)ncnc12

InChI Key InChIKey=PKLZLGDDUXRMPL-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457775   

LigandPNGBDBM457775(2-amino-9-[(1R,6R,8R,9R,14S,16R,17R,18R)-16- (6-am...)
Affinity DataEC50:  2.30nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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Date in BDB:
4/4/2021
Entry Details
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