BDBM457771 2-amino-9-[(1R,6S,8R,9R,14R,16R,17R)-16-(6- amino-9H-purin-9-yl)-3,11,17-trihydroxy-3,11- dioxido-2,4,7,10,12,15-hexaoxa-3,11- diphosphatricyclo[12.2.1.16,9]octadec-8-yl]-1,9- dihydro-6H-purin-6-one::US10738074, Example 2

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H]2C[C@H]1OP(O)(=O)OC[C@H]1O[C@H]([C@H](OP(O)(=O)OC2)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=ADHMHLOWAYZCPG-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457771   

LigandPNGBDBM457771(2-amino-9-[(1R,6S,8R,9R,14R,16R,17R)-16-(6- amino-...)
Affinity DataEC50:  18.2nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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Date in BDB:
4/4/2021
Entry Details
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