BDBM457113 US10738053, Example 4.00::US10738053, Example 4.01::US10738053, Example 4.02::US10738053, Example 4.03::US10738053, Example 5.00::US10738053, Example 5.01::US10738053, Example 5.02::US10738053, Example 5.03
SMILES C[C@]12CN(C[C@@H]1CN(C2)C(=O)OCc3ccc(cc3)OC(F)(F)F)C(=O)c4ccc(cc4)S(=O)(=O)N
InChI Key InChIKey=BGHGKELMYMNCFY-UHFFFAOYSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 457113
Affinity DataIC50: 6nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair