BDBM457097 US10738053, Example 1.00::US10738053, Example 1.01::US10738053, Example 1.02::US10738053, Example 1.03::US10738053, Example 1.04::US10738053, Example 1.05::US10738053, Example 1.06::US10738053, Example 1.07::US10738053, Example 1.08::US10738053, Example 1.09
SMILES CO[C@]12CN(C[C@@H]1CN(C2)C(=O)c1ccc(cc1F)S(N)(=O)=O)C(=O)OCc1ncc(cc1NC(=O)C(C)(C)C)C(F)(F)F
InChI Key InChIKey=FQSCYWBLDBNLFI-UHFFFAOYSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 457097
Affinity DataIC50: 8nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Human ATX: Assay working solutions were made as follows: Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:CA-II: Assay working solutions were made as follows:Assay buffer: 50 mM MOPS, 33 mM Na2SO4, 1 mM EDTA, 0.5 mg/ml BSA, pH 7.5; Enzyme solution: hCA-II...More data for this Ligand-Target Pair