BDBM457047 US10738015, Example SC-11::trans-5-(5-(cyclobutylmethyl)- 2-(dimethylamino)-6-oxo-2- phenyl-5,7- diazaspiro[3.4]octan-7-yl)-4- methoxypyrimidine-2- carbonitrile

SMILES COc1nc(ncc1N1C[C@]2(C[C@](C2)(N(C)C)c2ccccc2)N(CC2CCC2)C1=O)C#N

InChI Key InChIKey=OMWVZAUUCVNDMM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457047   

TargetMu-type opioid receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM457047(trans-5-(5-(cyclobutylmethyl)- 2-(dimethylamino)-6...)
Affinity DataKi:  3nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM457047(trans-5-(5-(cyclobutylmethyl)- 2-(dimethylamino)-6...)
Affinity DataKi:  99nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent