BDBM457043 US10738015, Example SC-7::trans-5-(cyclobutylmethyl)-2- (dimethylamino)-7-(2-(1,1- dioxidothiomorpholino)-2- oxoethyl)-2-phenyl-5,7- diazaspiro[3.4]octan-6-one

SMILES CN(C)[C@@]1(C[C@@]2(C1)CN(CC(=O)N1CCS(=O)(=O)CC1)C(=O)N2CC1CCC1)c1ccccc1

InChI Key InChIKey=IWQJQZWGTHDXNF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457043   

TargetMu-type opioid receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM457043(trans-5-(cyclobutylmethyl)-2- (dimethylamino)-7-(2...)
Affinity DataKi:  2nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM457043(trans-5-(cyclobutylmethyl)-2- (dimethylamino)-7-(2...)
Affinity DataKi:  230nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent