BDBM457040 US10738015, Example SC-4::trans-2-(dimethylamino)-7-(2- (1,1-dioxidothiomorpholino)- 2-oxoethyl)-2-phenyl-5,7- diazaspiro[3.4]octan-6-one

SMILES CN(C)[C@@]1(C[C@@]2(C1)CN(CC(=O)N1CCS(=O)(=O)CC1)C(=O)N2)c1ccccc1

InChI Key InChIKey=QEBKEPCUSRXOJF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457040   

TargetMu-type opioid receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM457040(trans-2-(dimethylamino)-7-(2- (1,1-dioxidothiomorp...)
Affinity DataKi:  15nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM457040(trans-2-(dimethylamino)-7-(2- (1,1-dioxidothiomorp...)
Affinity DataKi:  860nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent