BDBM457014 US10738007, Compound ID 80::US10738007, Compound ID 93::US11555039, Compound ID 80

SMILES COc1ccc(NC(=O)c2cccc(c2)[C@@H](CO)NC(=O)c2ccc(cc2)-c2ccncc2)cn1

InChI Key InChIKey=CKUIXZUZIPIFQX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 457014   

TargetRho-associated protein kinase 1(Human)
Translation Drug Development

US Patent
LigandPNGBDBM457014(US10738007, Compound ID 80 | US10738007, Compound ...)
Affinity DataIC50: 1.70nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Translation Drug Development

US Patent
LigandPNGBDBM457014(US10738007, Compound ID 80 | US10738007, Compound ...)
Affinity DataIC50: 0.510nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Translation Drug Development

US Patent
LigandPNGBDBM457014(US10738007, Compound ID 80 | US10738007, Compound ...)
Affinity DataIC50: 0.510nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetRho-associated protein kinase 1(Human)
Translation Drug Development

US Patent
LigandPNGBDBM457014(US10738007, Compound ID 80 | US10738007, Compound ...)
Affinity DataIC50: 1.70nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Translation Drug Development

US Patent
LigandPNGBDBM457014(US10738007, Compound ID 80 | US10738007, Compound ...)
Affinity DataIC50: 0.510nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent