BDBM456994 US10738007, Compound ID 60::US11555039, Compound ID 60

SMILES CC(C)N1CCC(CNC(=O)c2cccc(c2)[C@@H](C)NC(=O)c2ccc(cc2)-c2ccncc2)CC1

InChI Key InChIKey=PCYMBJXWBGCZAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456994   

TargetRho-associated protein kinase 2(Human)
Translation Drug Development

US Patent
LigandPNGBDBM456994(US10738007, Compound ID 60 | US11555039, Compound ...)
Affinity DataIC50: 0.530nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
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TargetRho-associated protein kinase 2(Human)
Translation Drug Development

US Patent
LigandPNGBDBM456994(US10738007, Compound ID 60 | US11555039, Compound ...)
Affinity DataIC50: 0.530nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent