BDBM456957 US10738007, Compound ID 21::US11555039, Compound ID 21

SMILES OC[C@@H](NC(=O)c1ccc(cc1)-c1ccncc1)c1cccc(c1)C(=O)NCC1CCCCC1

InChI Key InChIKey=MKSLDODSQFIWOS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 456957   

TargetRho-associated protein kinase 1(Human)
Translation Drug Development

US Patent
LigandPNGBDBM456957(US10738007, Compound ID 21 | US11555039, Compound ...)
Affinity DataIC50: 3.10nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Translation Drug Development

US Patent
LigandPNGBDBM456957(US10738007, Compound ID 21 | US11555039, Compound ...)
Affinity DataIC50: 1nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetRho-associated protein kinase 1(Human)
Translation Drug Development

US Patent
LigandPNGBDBM456957(US10738007, Compound ID 21 | US11555039, Compound ...)
Affinity DataIC50: 3.10nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Translation Drug Development

US Patent
LigandPNGBDBM456957(US10738007, Compound ID 21 | US11555039, Compound ...)
Affinity DataIC50: 1nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent