BDBM456913 US10736974, Compound XY-42::US10736974, Entry 16

SMILES OC(=O)CC[C@H](NC(=O)O[C@@H](CCCCNC(=O)c1ccc(cc1F)-c1ccccc1)OC=O)C(O)=O

InChI Key InChIKey=YBLXOZYDPLTDBK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 456913   

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM456913(US10736974, Entry 16 | US10736974, Compound XY-42)
Affinity DataIC50: 86nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM456913(US10736974, Entry 16 | US10736974, Compound XY-42)
Affinity DataKi:  13nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM456913(US10736974, Entry 16 | US10736974, Compound XY-42)
Affinity DataKi:  13nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent