BDBM456899 US10736974, Entry 6

SMILES COc1ccc2cc(ccc2c1)C(=O)NCCCC[C@@H](OC=O)OC(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=XLMQJRIQDDCJCD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456899   

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM456899(US10736974, Entry 6)
Affinity DataIC50: 104nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM456899(US10736974, Entry 6)
Affinity DataKi:  20nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent