BDBM456149 US10723723, Example 35

SMILES COc1c(CNC[C@H](O)c2ccc3C(=O)OCc3c2C)cnn1-c1cc(C)c(cn1)C#N

InChI Key InChIKey=SEXFZRGPLIRTBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456149   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM456149(US10723723, Example 35)
Affinity DataIC50: 1nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM456149(US10723723, Example 35)
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed