BDBM455778 N-[[6-(2,2- dimethylcyclopropanecarbonyl)- 6-azaspiro[2.5]octan-2- yl]methyl]furo[2,3-c]pyndine-2- carboxamide::US10730889, Example 373

SMILES CC1(C)CC1C(=O)N1CCC2(CC2CNC(=N)c2cc3ccncc3o2)CC1

InChI Key InChIKey=YVPJFNAHSSXTOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455778   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM455778(N-[[6-(2,2- dimethylcyclopropanecarbonyl)- 6-azasp...)
Affinity DataIC50: 15.2nMAssay Description:NAMPT Protein Purification. Recombinant His-tagged NAMPT was produced in E. coli cells, purified over a Ni column, and further purified over a size-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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