BDBM455767 N-[[6-[4-(4-methylpiperazin-1- yl)benzoyl]-6- azaspiro[2.5]octan-2-yl]methyl]- 1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide::US10730889, Example 362

SMILES CCN(CCCCCCNC(=O)N1CC\C(C1)=C/N=C\C)C(=O)c1ccc(cc1)N1CCN(C)CC1

InChI Key InChIKey=ZDONVTPOAABGRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455767   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM455767(N-[[6-[4-(4-methylpiperazin-1- yl)benzoyl]-6- azas...)
Affinity DataIC50: 9.69nMAssay Description:NAMPT Protein Purification. Recombinant His-tagged NAMPT was produced in E. coli cells, purified over a Ni column, and further purified over a size-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
Go to US Patent