BDBM455761 N-[[6-[2-(1,4-dimethyl-4- piperidyl)acetyl]-6- azaspiro[2.5]octan-2-yl]methyl]- 1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide::US10730889, Example 356

SMILES CCC1(CCNC(=O)CC2(C)CCN(C)CC2)CC1CNC(=O)N1CC2CN=CC=C2C1

InChI Key InChIKey=SARLXADWSHHKMR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455761   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM455761(N-[[6-[2-(1,4-dimethyl-4- piperidyl)acetyl]-6- aza...)
Affinity DataIC50: 6nMAssay Description:NAMPT Protein Purification. Recombinant His-tagged NAMPT was produced in E. coli cells, purified over a Ni column, and further purified over a size-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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