BDBM455702 N-[[6-(1-benzyl-3,5-dimethyl- pyrazole-4-carbonyl)-6- azaspiro[2.5]octan-2- yl]methyl]furo[2,3-c]pyridine-2- carboxamide::US10730889, Example 295

SMILES CCN(CCC1CC1CNC(=O)c1cc(\C=C/N=C)co1)C(=O)c1c(C)nn(Cc2ccccc2)c1C

InChI Key InChIKey=AAEGJGHAZOCBJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455702   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM455702(N-[[6-(1-benzyl-3,5-dimethyl- pyrazole-4-carbonyl)...)
Affinity DataIC50: 14.5nMAssay Description:NAMPT Protein Purification. Recombinant His-tagged NAMPT was produced in E. coli cells, purified over a Ni column, and further purified over a size-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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