BDBM455697 N-[[6-(3-tetrahydropyran-4- ylpropanoyl)-6- azaspiro[2.5]octan-2-yl]methyl]- 1,3-dihydropyrrolo(3,4- c]pyridine-2-carboxamide::US10730889, Example 290

SMILES CCC1(CCNC(=O)CCC2CCOCC2)CC1CNCN1Cc2ccncc2C1

InChI Key InChIKey=ZYKBGENODXYCKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455697   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM455697(N-[[6-(3-tetrahydropyran-4- ylpropanoyl)-6- azaspi...)
Affinity DataIC50: 4.54nMAssay Description:NAMPT Protein Purification. Recombinant His-tagged NAMPT was produced in E. coli cells, purified over a Ni column, and further purified over a size-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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