BDBM455687 N-[[6-[4-(2-methyltetrazol-5- y])benzoyl]-6- azaspiro[2.5]octan-2- yl]methyl]furo[2,3-c]pyridine-2- carboxamide::US10730889, Example 280

SMILES Cn1nnc(n1)-c1ccc(cc1)C(=O)N1CCC2(CC2CNC(=O)c2cc3ccncc3o2)CC1

InChI Key InChIKey=KYBDSTXGQNYJTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455687   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM455687(N-[[6-[4-(2-methyltetrazol-5- y])benzoyl]-6- azasp...)
Affinity DataIC50: 15.2nMAssay Description:NAMPT Protein Purification. Recombinant His-tagged NAMPT was produced in E. coli cells, purified over a Ni column, and further purified over a size-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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