BDBM455616 US10730889, Example 204::[2,2,2-trideuteno-1,1- bis(trideuteriomethyl]ethyl] 2- [(1,3-dihydropyrrolo[3,4- c]pyridine-2- carbonylamino)methyl]-6- azaspiro[2.5]octane-6- carboxylate

SMILES CCN(CCC1CC1CNC(=O)N1Cc2ccncc2C1)C(=O)OC(C)(C)C

InChI Key InChIKey=LMTQFRCTKTYOEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455616   

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandPNGBDBM455616(US10730889, Example 204 | [2,2,2-trideuteno-1,1- b...)
Affinity DataIC50: 6.36nMAssay Description:NAMPT Protein Purification. Recombinant His-tagged NAMPT was produced in E. coli cells, purified over a Ni column, and further purified over a size-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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