BDBM455368 ((R)-1-(4-Fluoro-phenyl)-::US10730882, Example 4

SMILES C[C@@H](Nc1ncc2cc(ccc2n1)-c1ncnc2[nH]ncc12)c1ccc(F)cc1

InChI Key InChIKey=PVSMUQHUDTWVDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455368   

TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455368(US10730882, Example 4 | ((R)-1-(4-Fluoro-phenyl)-)
Affinity DataIC50: 22nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
Go to US Patent