BDBM45489 (8S,8aR,11aS,11bS)-10-(4-Methoxy-phenyl)-9,11-dioxo-8a,9,10,11,11a,11b-hexahydro-8H-pyrrolo[3', 4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylic acid phenylamide::MLS000557352::SMR000148269::cid_6357416

SMILES [H][C@]12[C@H](N3C=Cc4ccccc4[C@]3([H])[C@@]1([H])C(=O)N(C2=O)c1ccc(OC)cc1)C(=O)Nc1ccccc1

InChI Key InChIKey=BBCDVTQRQLUUFI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 45489   

TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM45489(MLS000557352 | (8S,8aR,11aS,11bS)-10-(4-Methoxy-ph...)
Affinity DataIC50: 3.72E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM45489(MLS000557352 | (8S,8aR,11aS,11bS)-10-(4-Methoxy-ph...)
Affinity DataIC50: 3.72E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetCaspase-3(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM45489(MLS000557352 | (8S,8aR,11aS,11bS)-10-(4-Methoxy-ph...)
Affinity DataIC50: 1.24E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM45489(MLS000557352 | (8S,8aR,11aS,11bS)-10-(4-Methoxy-ph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay