BDBM453731 US10730863, Example 36

SMILES COC(=O)c1cccc(c1)-c1noc(n1)C12CCC(CC1)(CC2)OCc1c(noc1C1CC1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=WLJZSKDVUWJILT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453731   

TargetBile acid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM453731(US10730863, Example 36)
Affinity DataEC50:  3.50E+3nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent