BDBM453727 US10730863, Example 32

SMILES Clc1cccc(Cl)c1-c1noc(C2CC2)c1COC12CCC(CC1)(CC2)c1nc(no1)-c1ccc(cc1)C(=O)NS(=O)(=O)c1ccccc1

InChI Key InChIKey=PEDNHFLGOMRXRQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453727   

TargetBile acid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM453727(US10730863, Example 32)
Affinity DataEC50:  300nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent