BDBM453399 4-{6-[3-(tetrahydro-2H-pyran-4-yl)propoxy]-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl}butanoic Acid::US10730830, Example 18 (42)

SMILES OC(=O)CCCN1CCc2cccc(OCCCC3CCOCC3)c2CC1

InChI Key InChIKey=RNKWSERYNRJVPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453399   

TargetSphingosine 1-phosphate receptor 5(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453399(4-{6-[3-(tetrahydro-2H-pyran-4-yl)propoxy]-1,2,4,5...)
Affinity DataIC50: 550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453399(4-{6-[3-(tetrahydro-2H-pyran-4-yl)propoxy]-1,2,4,5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent