BDBM453392 4-[7-Methyl-6-(3-phenylpropoxy)-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl]butanoic Acid::US10730830, Example 29

SMILES Cc1ccc2CCN(CCCC(O)=O)CCc2c1OCCCc1ccccc1

InChI Key InChIKey=UPGSKNJOXKPLSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453392   

TargetSphingosine 1-phosphate receptor 5(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453392(4-[7-Methyl-6-(3-phenylpropoxy)-1,2,4,5-tetrahydro...)
Affinity DataIC50: 50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453392(4-[7-Methyl-6-(3-phenylpropoxy)-1,2,4,5-tetrahydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent