BDBM453390 1-[8-(3-Phenylpropoxy)-1,2,3,4-tetrahydro-2-naphthalenyl]-3-azetidinecarboxylic Acid::US10730830, Example 3 (4)

SMILES OC(=O)C1CN(C1)C1CCc2c(C1)cccc2OCCCc1ccccc1

InChI Key InChIKey=UHPPLJKGPABMEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453390   

TargetSphingosine 1-phosphate receptor 5(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453390(1-[8-(3-Phenylpropoxy)-1,2,3,4-tetrahydro-2-naphth...)
Affinity DataIC50: 50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453390(1-[8-(3-Phenylpropoxy)-1,2,3,4-tetrahydro-2-naphth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent