BDBM453388 4-{6-[(5-Phenylpentyl)oxy]-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl}butanoic Acid::US10730830, Example 18 (24)

SMILES OC(=O)CCCN1CCc2cccc(OCCCCCc3ccccc3)c2CC1

InChI Key InChIKey=PMHYEZFJGIGWSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453388   

TargetSphingosine 1-phosphate receptor 5(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453388(4-{6-[(5-Phenylpentyl)oxy]-1,2,4,5-tetrahydro-3H-3...)
Affinity DataIC50: 50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453388(4-{6-[(5-Phenylpentyl)oxy]-1,2,4,5-tetrahydro-3H-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent