BDBM453380 US10730830, Example 49

SMILES OC(=O)CCCCN1CCCc2c(C1)cccc2OC\C=C\c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UYGRWBIYPDURAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453380   

TargetSphingosine 1-phosphate receptor 5(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453380(US10730830, Example 49)
Affinity DataIC50: 2.00E+3nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453380(US10730830, Example 49)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent