BDBM453353 BDBM553857::US10730826, Compound 43a

SMILES NCCCCC(NC(=O)c1cccnc1)C(=O)COc1c(F)cccc1F

InChI Key InChIKey=CAVMOPMUEYTETG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453353   

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453353(BDBM553857 | US10730826, Compound 43a)
Affinity DataIC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453353(BDBM553857 | US10730826, Compound 43a)
Affinity DataIC50: 0.0900nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/14/2022
Entry Details
Go to US Patent