BDBM453322 4-{5-[2-(2-naphthyl)ethoxy]-3,4-dihydro-2(1H)-isoquinolinyl}butanoic Acid::US10730830, Example 18 (1)

SMILES OC(=O)CCCc1cccc2CN(CCc12)c1ccc2ccccc2c1

InChI Key InChIKey=ATHPUMZOPARQFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453322   

TargetSphingosine 1-phosphate receptor 5(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453322(4-{5-[2-(2-naphthyl)ethoxy]-3,4-dihydro-2(1H)-isoq...)
Affinity DataIC50: 2.00E+3nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM453322(4-{5-[2-(2-naphthyl)ethoxy]-3,4-dihydro-2(1H)-isoq...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent