BDBM453221 US10729691, Example 6

SMILES O=C(COc1cccc(c1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2sccc2n1)NC1CCC1

InChI Key InChIKey=CIIAIZAOSYXJCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453221   

LigandPNGBDBM453221(US10729691, Example 6)
Affinity DataIC50: 175nMAssay Description:HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetPutative sugar transporter(malaria parasite P. falciparum)
Kadmon

US Patent
LigandPNGBDBM453221(US10729691, Example 6)
Affinity DataIC50: 55nMAssay Description:Parasite cultures were seeded in 96-well plates (1% hematocrit, 1-2% starting parasitemia, 100 μL total volume) with varying concentrations of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent