BDBM453027 (2S,3S,4R,5R)-2-((S)-2- chloro-4,7-dihydro-5H- thieno[2,3-c]pyran-7-yl)-5-(4- methyl-7H-pyrrolo[2,3- d]pyrimidin-7- yl)tetrahydrofuran-3,4-diol::US10711007, Example 89::US11214574, Ex# 89::US11254683, Example 89
SMILES Cc1ncnc2n(ccc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)[C@@H]1OCCc2cc(Cl)sc12
InChI Key InChIKey=RGEFRBMOBQDZBB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 453027
Affinity DataIC50: 15.7nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataIC50: 15.7nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Affinity DataIC50: 15.7nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair