BDBM452956 7-methyl-1-[[3- [(1S,5S,6R)-3-(1,3- benzothiazol-6-yl)-6- bicyclo[3.1.0]hex-2- enyl]-1,2,4-oxadiazol- 5-yl]methyl]purin-6-one::US10711004, Example 278

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CC(=C[C@@H]34)c3ccc4ncsc4c3)c(=O)c12

InChI Key InChIKey=AGPQIQSLJAQASS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452956   

LigandPNGBDBM452956(7-methyl-1-[[3- [(1S,5S,6R)-3-(1,3- benzothiazol-6...)
Affinity DataIC50: 15.8nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452956(7-methyl-1-[[3- [(1S,5S,6R)-3-(1,3- benzothiazol-6...)
Affinity DataIC50: 3.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent