BDBM452947 7-methyl-1-[[3- [(1S,5S,6R)-3-(2,4- difluorophenyl)-6- bicyclo[3.1.0] hex-2-enyl]-1,2,4- oxadiazol-5-yl] methyl]purin-6-one::US10711004, Example 269

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CC(=C[C@@H]34)c3ccc(F)cc3F)c(=O)c12

InChI Key InChIKey=HQOTZKAHXGIKLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452947   

LigandPNGBDBM452947(7-methyl-1-[[3- [(1S,5S,6R)-3-(2,4- difluorophenyl...)
Affinity DataIC50: 6.96nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452947(7-methyl-1-[[3- [(1S,5S,6R)-3-(2,4- difluorophenyl...)
Affinity DataIC50: 4.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent