BDBM452939 7-amino-3-[[3- [(1R,5S)-3-(3- fluorophenyl)-3- azabicyclo[3.1.0] hexan-6-yl]-1,2,4- oxadiazol-5-yl] methyl]pyrido[2,3-::US10711004, Example 261

SMILES Nc1ccc2c(ncn(Cc3nc(no3)[C@@H]3[C@H]4CN(C[C@@H]34)c3cccc(F)c3)c2=O)n1

InChI Key InChIKey=AIXGIOZVDSOSEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452939   

LigandPNGBDBM452939(7-amino-3-[[3- [(1R,5S)-3-(3- fluorophenyl)-3- aza...)
Affinity DataIC50: 9.73nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452939(7-amino-3-[[3- [(1R,5S)-3-(3- fluorophenyl)-3- aza...)
Affinity DataIC50: 4.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent