BDBM452926 1-[[3-[trans-3- [difluoro-(3- fluorophenyl)methyl] cyclobutyl]-1,2,4- oxadiazol-5-yl] methyl]-7-methyl- purin-6-one::US10711004, Example 248

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@H]3C[C@H](C3)C(F)(F)c3cccc(F)c3)c(=O)c12

InChI Key InChIKey=DKSDOKBELUNFIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452926   

LigandPNGBDBM452926(1-[[3-[trans-3- [difluoro-(3- fluorophenyl)methyl]...)
Affinity DataIC50: 11.1nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452926(1-[[3-[trans-3- [difluoro-(3- fluorophenyl)methyl]...)
Affinity DataIC50: 5.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent