BDBM452917 7-amino-3-[[3- [(1S,5S,6R)-3-phenyl- 6-bicyclo[3.1.0]hex-2- enyl]-1,2,4-oxadiazol- 5-yl]methyl]pyrido[2,3- d]pyrimidin-4-one::US10711004, Example 239

SMILES Nc1ccc2c(ncn(Cc3nc(no3)[C@@H]3[C@H]4CC(=C[C@@H]34)c3ccccc3)c2=O)n1

InChI Key InChIKey=FTOLOGKZFWYVKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452917   

LigandPNGBDBM452917(7-amino-3-[[3- [(1S,5S,6R)-3-phenyl- 6-bicyclo[3.1...)
Affinity DataIC50: 10.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent

LigandPNGBDBM452917(7-amino-3-[[3- [(1S,5S,6R)-3-phenyl- 6-bicyclo[3.1...)
Affinity DataIC50: 5.30nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent