BDBM452914 1-((3-((1R,5S,6r)-3- (3-chloro-2-fluoro- phenyl)-3-azabicyclo [3.1.0]hexan-6-yl)- 1,2,4-oxadiazol-5-yl) methyl)-7-methyl- 1,7-dihydro-6H- purin-6-one::US10711004, Example 236

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CN(C[C@@H]34)c3cccc(Cl)c3F)c(=O)c12

InChI Key InChIKey=WZQMWEAVTLSMOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452914   

LigandPNGBDBM452914(1-((3-((1R,5S,6r)-3- (3-chloro-2-fluoro- phenyl)-3...)
Affinity DataIC50: 21.3nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452914(1-((3-((1R,5S,6r)-3- (3-chloro-2-fluoro- phenyl)-3...)
Affinity DataIC50: 4.40nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent