BDBM452786 1-methyl-6-((3- ((1S,5S,6R)-3- phenylbicyclo[3.1.0] hex-2-en-6-yl)-1,2,4- oxadiazol-5-yl) methyl)-1,6-dihydro- 7H-[1,2,3]triazolo::US10711004, Example 108

SMILES Cn1nnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CC(=C[C@@H]34)c3ccccc3)c(=O)c12

InChI Key InChIKey=LRZQMDHWCOUOPM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452786   

LigandPNGBDBM452786(1-methyl-6-((3- ((1S,5S,6R)-3- phenylbicyclo[3.1.0...)
Affinity DataIC50: 6.12nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452786(1-methyl-6-((3- ((1S,5S,6R)-3- phenylbicyclo[3.1.0...)
Affinity DataIC50: 3.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent